Galectin-1, human recombinant protein
Galectin-1, Lectin galactoside-binding soluble 1, β-galactoside- binding lectin L-14-I, Lactose-bind
|Calculated MW||14.5 kDa|
|Other Names||Galectin-1, Lectin galactoside-binding soluble 1, β-galactoside- binding lectin L-14-I, Lactose-binding lectin 1, S-Lac lectin 1, Galaptin, 14 kDa lectin, HPL, HBL, Putative MAPK-activating protein PM12, GBP, DKFZp686E23103|
|Application Notes||Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°for future use.|
|Storage||-20°C; Sterile filtered and lyophilized from 20 mM Tris, pH 7.5.|
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Provided below are standard protocols that you may find useful for product applications.
Galectin-1 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of β-galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs). Galectin-1 has the ability to induce apoptosis of activated T-cells and T-leukaemia cell lines. Other activities include cell differentiation and inhibition activity of CD45 protein phosphatase activity. Galectin also binds β-galactoside as well as CD45, CD3 and CD4. Recombinant Human Galectin is a 14.5 kDa protein consisting of 134 amino acid residues.
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Than N.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:15819-15824(2008).
Gitt M.A.,et al.Biochemistry 30:82-89(1991).
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