PTHrP, human recombinant protein
PTH/PTHrP receptor antagonist, PTHrP analog, PTHR, MGC138426, MGC138452
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P12272 |
---|---|
Calculated MW | 9.8 kDa |
Gene ID | 5744 |
---|---|
Gene Symbol | PTHLH |
Other Names | PTH/PTHrP receptor antagonist, PTHrP analog, PTHR, MGC138426, MGC138452 |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; ≥98% |
Recombinant | Yes |
Target/Specificity | PTHrP |
Application Notes | Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers |
Format | Lyophilized protein |
Storage | -20°C; Sterile filtered and lyophilized with no additives |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Parathyroid Hormone-like related Protein (PTHrP) is a member of the Parathyroid hormone family that is expressed in the mammary gland. It is known as a potent inhibitor of chondrocyte maturation. PTHrP is expressed by periarticular perichondrial cells and exerts its biological activity on PP-R expressing cells. During endochondral bone development PTHrP plays a major role in suppressing the onset of hypertrophic differentiation. It is also responsible for most cases of humoral hypercalcemia of malignancy. Recombinant Human PTHrP is a 9.8 kDa protein consisting of 86 amino acid residues.
References
Suva L.J.,et al.Science 237:893-896(1987).
Mangin M.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:597-601(1988).
Yasuda T.,et al.J. Biol. Chem. 264:7720-7725(1989).
Thiede M.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:4605-4609(1988).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.