|Calculated MW||37660 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of active Cathepsin L-cleaved. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C|
|Other Names||Cathepsin L1, 18.104.22.168, Cathepsin L, Cyclic protein 2, CP-2, Major excreted protein, MEP, Procathepsin L, Cathepsin L1 heavy chain, Cathepsin L1 light chain, Ctsl, Ctsl1|
|Target/Specificity||Cathepsin L (Cleaved)|
|Formulation||50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||Cathepsin L (Cleaved) Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Important for the overall degradation of proteins in lysosomes. Procathepsin L is required for maximal stimulation of steroidogenesis by TIMP1.|
|Tissue Location||Both mature cathepsin L1 and procathepsin L are found in the upper epidermis. The lower epidermis predominantly contains procathepsin L. In seminiferous tubules expression is greater at stages VI-VII than at stages IX-XII|
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