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BMP-14/GDF-5, human recombinant protein

Cartilage-derived morphogenetic protein-1, Cartilage-Derived Morphogenetic Protein-1, CDMP-1, LAP4,

Product info
Primary Accession P43026
Calculated MW 26.8 kDa
Additional Info
Gene ID 8200
Gene Symbol GDF5
Other Names Cartilage-derived morphogenetic protein-1, Cartilage-Derived Morphogenetic Protein-1, CDMP-1, LAP4, SYNS2, Radotermin, CDMP1, GDF5, Growth differentiation factor 5, BMP-14
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC; ≥95%
Recombinant Yes
Results 30-50 nM
Application Notes Reconstitute in 20 Mm HOAc to a concentration of 0.1 to 1.0 mg/ml. This solution can then be diluted into other aqueous buffers
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized with no additives
Citations (0)

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GDF-5 acts as an inhibitor of nerve tissue growth. It is produced as a homodimer, non-glycosylated polypeptide chain containing 2 X 117 amino acids with a molecular weight of 26.8 kDa. To enable bacterial expression of rhGDF-5 we removed the N-terminal sequence Ala-Pro- Leu- Thr and added the Lys.


Hoetten G.,et al.Biochem. Biophys. Res. Commun. 204:646-652(1994).
Chang S.,et al.J. Biol. Chem. 269:28227-28234(1994).
Deloukas P.,et al.Nature 414:865-871(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Triantafilou K.,et al.Nat. Immunol. 2:338-345(2001).

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$ 80.00
$ 1,500.00
$ 190.00
Cat# PBV10349r
(40 western blots)
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