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GPV1 Blocking Peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9HCN6 |
|---|---|
| Gene ID | 51206 |
| Calculated MW | 36866 Da |
| Gene ID | 51206 |
|---|---|
| Application & Usage | The peptide is used for blocking the antibody activity of GPVI. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C. |
| Other Names | Platelet glycoprotein VI, GPVI, Glycoprotein 6, GP6 |
| Target/Specificity | GPV1 |
| Formulation | 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | GPV1 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GP6 (HGNC:14388) |
|---|---|
| Function | Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2. |
| Cellular Location | [Isoform 1]: Cell membrane; Single-pass membrane protein |
| Tissue Location | Megakaryocytes and platelets. |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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