|Calculated MW||244.0 kDa|
|Other Names||H₂O₂:H₂O₂ oxidoreductase|
|Storage||-70°C; Frozen in 50 mM Tris-HCl, pH 8.0|
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Composed of four identical subunits each with a molecular weight of 59,700. Catalyzes the reaction 2H₂O₂ to H₂O+O₂. Catalase, along with the superoxides dismutase and glutathione peroxidase, controls the levels of oxygen-derived free radicals in mammalian cells, and together may function as a somatic oxidant defense.
Quan F.,et al.Nucleic Acids Res. 14:5321-5335(1986).
Bell G.I.,et al.Nucleic Acids Res. 14:5561-5562(1986).
Jin L.H.,et al.Free Radic. Biol. Med. 31:1509-1519(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
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