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Nectin-3/CD113 Blocking Peptide

Product Information
Primary Accession Q9NQS3
Gene ID 25945
Calculated MW 61002 Da
Additional Information
Gene ID 25945
Application & Usage The peptide is used for blocking the antibody activity of Nectin-3. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Nectin-3, CDw113, Poliovirus receptor-related protein 3, CD113, PVRL3, PRR3
Target/Specificity Nectin-3/CD113
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsNectin-3/CD113 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PVRL3
Synonyms PRR3
Function Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Cellular Location Cell membrane; Single-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane
Tissue Location Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines
Research Areas
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$ 95.00
Cat# PBV10371b
(40 western blots)
Availability: 5-7days
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