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IGF-BP1, human recombinant protein
IGF-BP1, human recombinant
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P08833 |
|---|---|
| Calculated MW | 28.8 kDa |
| Gene ID | 3484 |
|---|---|
| Gene Symbol | IBP1 |
| Other Names | IBP-1, IGF-Binding Protein 1, AFBP, PP12, IGF-BP25, hIGFBP-1, IGFBP-1. |
| Gene Source | Human |
| Source | Nso cells |
| Assay&Purity | SDS-PAGE; ≥98% |
| Assay2&Purity2 | HPLC; ≥98% |
| Recombinant | Yes |
| Results | ~100 ng/ml |
| Application Notes | Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized with no additives |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Human IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, decidual, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, whereas nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a single, glycosylated protein consisting of 218 amino acid residues.
References
Brinkman A.,et al.EMBO J. 7:2417-2423(1988).
Brewer M.T.,et al.Biochem. Biophys. Res. Commun. 152:1289-1297(1988).
Grundmann U.,et al.Nucleic Acids Res. 16:8711-8711(1988).
Julkunen M.,et al.FEBS Lett. 236:295-302(1988).
Lee Y.-L.,et al.Mol. Endocrinol. 2:404-411(1988).
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