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IGF-BP5, human recombinant protein

Insulin-like Growth Factor-Binding Protein5

Product info
Primary Accession P24593
Calculated MW 28. 6 kDa
Additional Info
Gene ID 3488
Gene Symbol IBP5
Other Names Insulin-like Growth Factor-Binding Protein5
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Results <0.3 mg/ml
Application Notes Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized from 10 mM Sodium Citrate solution, pH 3.0.
Citations (0)

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Human IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by Vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Studies show that IGF-BP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGF-BP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole body growth inhibition, and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.

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$ 525.00
$ 2,850.00
$ 190.00
Cat# PBV10376r
(40 western blots)
Availability: 5-7days
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