|Calculated MW||26.2 kDa|
|Other Names||Inhibin beta-1, FRP, FSH-releasing protein|
|Results||< 2 ng/mL|
|Sequence||MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS|
|Application Notes||Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water, which can then be further diluted to other aqueous solutions.|
|Storage||-20°C; Recombinant human Activin A is lyophilized with 0.02% TFA.|
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Provided below are standard protocols that you may find useful for product applications.
Activin A is a member of the TGFbeta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Human Activin A has 100% amino acid sequence identity to mouse, rat, porcine, bovine and feline proteins. Recombinant human Activin A is a non-glycosylated homodimer, containing two 117 amino acid chains, with a total molecular weight of 26.2 kDa.
Mason A.J.,et al.Biochem. Biophys. Res. Commun. 135:957-964(1986).
Murata M.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:2434-2438(1988).
Tanimoto K.,et al.DNA Seq. 2:103-110(1991).
Hillier L.W.,et al.Nature 424:157-164(2003).
Stewart A.G.,et al.FEBS Lett. 206:329-334(1986).
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