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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   FRS2 Blocking Peptide   

FRS2 Blocking Peptide

Product Information
Primary Accession Q8WU20
Other Accession NP_006645.3
Gene ID 10818
Calculated MW 57029 Da
Additional Information
Gene ID 10818
Application & Usage The peptide is used for blocking the antibody activity of FRS2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Fibroblast growth factor receptor substrate 2, FGFR substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1, FRS2
Target/Specificity FRS2
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsFRS2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FRS2
Function Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Cellular Location Endomembrane system. Note=Cytoplasmic, membrane-bound
Tissue Location Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis
Research Areas
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$ 95.00
Cat# PBV10382b
(40 western blots)
Availability: 5-7days
Bulk Size
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