PLGF-1, human recombinant protein
PIGF, PGF, PLGF 1, Placenta Growth Factor-1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | AAD30179 |
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Calculated MW | 29.7 kDa |
Gene ID | 5228 |
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Gene Symbol | PGF |
Other Names | PIGF, PGF, PLGF 1, Placenta Growth Factor-1 |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥95% |
Assay2&Purity2 | HPLC; ≥95% |
Recombinant | Yes |
Results | 0.5-10 ng/ml |
Application Notes | Reconstitute the protein in sterile 20 mM acetic acid to a concentration of 0.1-1.0 µg/ µl. The solution can then be diluted into other aqueous buffer |
Format | Lyophilized protein |
Storage | -20°C; Sterile filtered and lyophilized with no additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
PLGF (also called Placenta Growth Factor, PIGF, PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant mouse PLGF is a disulfide-linked homodimer containing two 142 amino acid polypeptide chains.
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