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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Furin/PACE Blocking Peptide   

Furin/PACE Blocking Peptide

Product Information
Primary Accession P23188
Other Accession NP_035176
Gene ID 18550
Calculated MW 86772 Da
Additional Information
Gene ID 18550
Application & Usage The peptide is used for blocking the antibody activity of Furin/PACE. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Furin,, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, PACE, Prohormone convertase 3, Furin, Fur, Pcsk3
Target/Specificity Furin/PACE
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsFurin/PACE Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Furin
Synonyms Fur, Pcsk3
Function Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
Cellular Location Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Note=Shuttles between the trans-Golgi network and the cell surface. Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin (By similarity)
Tissue Location Seems to be expressed ubiquitously.
Research Areas
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$ 95.00
Cat# PBV10402b
(40 western blots)
Availability: 5-7days
Bulk Size
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