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SCD Blocking Peptide

     
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Product Information
Primary Accession Q6P7B9
Other Accession NP_114029
Gene ID 83792
Calculated MW 41013 Da
Additional Information
Gene ID 83792
Application & Usage The peptide is used for blocking the antibody activity of SCD. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Acyl-CoA desaturase 2, 1.14.19.1, Delta(9)-desaturase 2, Delta-9 desaturase 2, Fatty acid desaturase 2, Stearoyl-CoA desaturase 2, Scd2
Target/Specificity SCD
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsSCD Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Scd2
Function Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides, especially during embryonic development and in neonates. Important for normal permeability barrier function of the skin in neonates.
Cellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P13011}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P13011}. Microsome membrane {ECO:0000250|UniProtKB:P13011}
Tissue Location Detected in brain and adipose tissue, and at much lower levels in testis. Detected in liver when rats are kept on a fat-free diet, but not when their food contains unsaturated fatty acids.
Research Areas
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$ 95.00
Cat# PBV10404b-50
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