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D4-GDI, human recombinant protein

D4-GDI, D4GDI, Rho GDP dissociation inhibitor (GDI) α

Product info
Primary Accession P52565
Concentration 0.1
Calculated MW 54 kDa
Additional Info
Gene ID 396
Gene Symbol ARHGDIA
Other Names D4-GDI, D4GDI, Rho GDP dissociation inhibitor (GDI) α
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC; ≥90%
Recombinant Yes
Format Liquid
Storage -20°C; Sterile filtered liquid (100 µg/ml) in 50mM Tris-Acetate, pH 7.5, 1mM EDTA, 20% Glycerol.
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D4-GDI belongs to the family of rho-GDI or GDP-dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of rhoGDI-1, D4-GDI/rhoGDI-2 and rhoGDI-3. It inhibits the release of GDP from the Rho proteins, essential for GTP-loading and activation of GTPase activity. D4-GDI is located in the cytoplasm and is involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas-mediated apoptosis.

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$ 495.00
Cat# PBV10422r
(40 western blots)
Availability: 5-7days
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