|Calculated MW||53.0 kDa|
|Other Names||HGNC:11998, Cys51Stop, TRP53, p53 , Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53|
|Storage||-20°C; 1 mg/ml in 50 mM Tris-Acetate, pH 7.5, 1 mM EDTA, and 20% Glycerol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma. Recombinant human p53 protein purified by proprietary chromatographic techniques.
Zakut-Houri R.,et al.EMBO J. 4:1251-1255(1985).
Lamb P.,et al.Mol. Cell. Biol. 6:1379-1385(1986).
Harlow E.,et al.Mol. Cell. Biol. 5:1601-1610(1985).
Harris N.,et al.Mol. Cell. Biol. 6:4650-4656(1986).
Buchman V.L.,et al.Gene 70:245-252(1988).
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