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EDEM1 Blocking Peptide

Product Information
Primary Accession Q925U4
Gene ID 192193
Calculated MW 73701 Da
Additional Information
Gene ID 192193
Application & Usage The peptide is used for blocking the antibody EDEM1. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names ER degradation-enhancing alpha-mannosidase-like protein 1, Edem1, Edem
Target/Specificity EDEM1
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsEDEM1 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Edem1
Synonyms Edem
Function Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Research Areas
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$ 95.00
Cat# PBV10428b
(40 western blots)
Availability: 5-7days
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