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ICAM-2 Blocking Peptide

     
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Product Information
Primary Accession P35330
Gene ID 15896
Calculated MW 31390 Da
Additional Information
Gene ID 15896
Application & Usage The peptide is used for blocking the antibody activity of ICAM-2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Intercellular adhesion molecule 2, ICAM-2, Lymphocyte function-associated AG-1 counter-receptor, CD102, Icam2, Icam-2
Target/Specificity ICAM-2
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsICAM-2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Icam2
Synonyms Icam-2
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Cellular Location Membrane; Single-pass type I membrane protein. Cell projection, microvillus. Note=Co-localizes with RDX, EZR and MSN in microvilli.
Tissue Location Expressed in endothelial cells and leukocytes. High levels found in lung
Research Areas
Citations (0)
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Discontinued
Cat# PBV10439b-50
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