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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PAK6 Blocking Peptide   

PAK6 Blocking Peptide

Product Information
Primary Accession Q3ULB5
Other Accession AAI50755
Gene ID 214230
Calculated MW 74867 Da
Additional Information
Gene ID 214230
Application & Usage The peptide is used for blocking the antibody activity of Pak6. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Serine/threonine-protein kinase PAK 6,, p21-activated kinase 6, PAK-6, Pak6
Target/Specificity PAK6
Formulation 50 µg (0.5mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPAK6 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pak6
Function Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Cotranslocates into nucleus with AR in response to androgen induction.
Research Areas
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$ 95.00
Cat# PBV10440b
(40 western blots)
Availability: 5-7days
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