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ALK7 Blocking Peptide

     
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Product Information
Primary Accession Q8K348
Gene ID 269275
Calculated MW 54700 Da
Additional Information
Gene ID 269275
Application & Usage The peptide is used for blocking the antibody activity of ALK7. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Activin receptor type-1C, 2.7.11.30, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7, Acvr1c {ECO:0000312|EMBL:AAH28780.1}
Target/Specificity ALK7
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsALK7 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Acvr1c {ECO:0000312|EMBL:AAH28780.1}
Function Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in interdigital regions in developing limb buds.
Research Areas
Citations (0)
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Discontinued
Cat# PBV10450b-50
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