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AdipoR1 Blocking Peptide

     
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Product Information
Primary Accession Q91VH1
Other Accession EDL39610
Gene ID 72674
Calculated MW 42366 Da
Additional Information
Gene ID 72674
Application & Usage The peptide is used for blocking the antibody activity of AdipoR1. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Adiponectin receptor protein 1, Adipor1
Target/Specificity AdipoR1
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsAdipoR1 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Adipor1
Function Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:17327425, PubMed:17268472, PubMed:24742672). Required for normal glucose and fat homeostasis and for maintaining a normal body weight (PubMed:17327425, PubMed:24742672). ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis (PubMed:12802337, PubMed:17327425, PubMed:17268472, PubMed:24742672). Has high affinity for globular adiponectin and low affinity for full-length adiponectin (PubMed:12802337).
Cellular Location Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q96A54} Note=Localized to the cell membrane and intracellular organelles {ECO:0000250|UniProtKB:Q96A54}
Tissue Location Detected in brain and quadriceps muscle (at protein level) (PubMed:17327425). Widely expressed (PubMed:12802337). Expressed in heart, kidney, liver, lung, skeletal muscle, white adipose tissue, brown adipose tissue, aorta and spleen (PubMed:12802337, PubMed:24742672). Weakly expressed in brain and testis (PubMed:12802337).
Research Areas
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$ 95.00
Cat# PBV10452b
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