|Calculated MW||55596 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of Perilipin A. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.|
|Other Names||Perilipin-1, Lipid droplet-associated protein, Perilipin A, Plin1, Peri, Plin|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||Perilipin A Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness (By similarity). Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.|
|Cellular Location||Endoplasmic reticulum. Lipid droplet. Note=Lipid droplet surface- associated|
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