|Calculated MW||97476 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of AMPK. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.|
|Other Names||3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase, 184.108.40.206, HMGCR|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||HMG-CoA Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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