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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TORC2 Blocking Peptide   

TORC2 Blocking Peptide

Product Information
Primary Accession Q3LRZ1
Other Accession NP_001029067.1
Gene ID 310615
Calculated MW 73146 Da
Additional Information
Gene ID 310615
Application & Usage The peptide is used for blocking the antibody activity of TORC2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, TORC-2, Transducer of CREB protein 2, Crtc2, Torc2
Target/Specificity TORC2
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTORC2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Crtc2
Synonyms Torc2
Function Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Translocated from the nucleus to the cytoplasm on interaction of the phosphorylated form with 14-3-3 protein. In response to cAMP levels and glucagon, relocated to the nucleus (By similarity).
Research Areas
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$ 95.00
Cat# PBV10465b
(40 western blots)
Availability: 5-7days
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