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Rictor Blocking Peptide

Product Information
Primary Accession Q6QI06
Other Accession NP_084444
Gene ID 78757
Calculated MW 191570 Da
Additional Information
Gene ID 78757
Application & Usage The peptide is used for blocking the antibody activity of Rictor. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Rapamycin-insensitive companion of mTOR, AVO3 homolog, mAVO3, Protein pianissimo, Rictor {ECO:0000250|UniProtKB:Q6R327}
Target/Specificity Rictor
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsRictor Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rictor {ECO:0000250|UniProtKB:Q6R327}
Function Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient- insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development.
Research Areas
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$ 95.00
Cat# PBV10469b
(40 western blots)
Availability: 5-7days
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