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HDJ1, human recombinant protein

HSP-40, HSP40, DnaJ, DNAJB1, HSPF1, Hdj1, DnaJ homolog subfamily B member 1, Heat shock 40 kDa prote

Product info
Primary Accession P25685
Calculated MW 38044 Da
Additional Info
Gene ID 3337
Gene Symbol DNJB1
Other Names HSP-40, HSP40, DnaJ, DNAJB1, HSPF1, Hdj1, DnaJ homolog subfamily B member 1, Heat shock 40 kDa protein 1, Heat shock protein 40, DnaJ protein homolog 1, HDJ-1, Sis1.
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC; ≥95%
Recombinant Yes
Format Liquid
Storage -80°C; In 50 mM Tris-HCl, pH 7.7, containing 100 mM potassium chloride
Citations (0)

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Hsp40/Hdj1 is a cytosolic co-chaperone belonging to the class DnaJ, named after its homolog in E. coli. Hsp40 functions in protein folding by binding nascent peptides and unfolded substrates and facilitating substrate interaction with Hsp70. Binding of Hsp40 to Hsp70 increases Hsp70 ATP hydrolysis and substrate binding, which is reversed by the action of nucleotide exchange factors (GrpE in E. coli). Repeated cycles of Hsp40/Hsp70 peptide binding and ATP hydrolysis prevent premature folding and aggregation, promoting protein maturation throughout the cell.


Raabe T.,et al.Nucleic Acids Res. 19:6645-6645(1991).
Ohtsuka K.,et al.Biochem. Biophys. Res. Commun. 197:235-240(1993).
Hata M.,et al.Genomics 38:446-449(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).

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$ 275.00
Cat# PBV10471r
(40 western blots)
Availability: 5-7days
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