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Nesfatin-1, mouse recombinant protein
Nesfatin 1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P81117 |
|---|---|
| Calculated MW | 8.0 kDa |
| Gene ID | 53322 |
|---|---|
| Gene Symbol | Nucb2 |
| Other Names | Nesfatin 1, Nucleobindin-2, DNA-binding protein NEFA, Prepronefastin |
| Gene Source | Mouse |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; |
| Recombinant | Yes |
| Application Notes | Reconstitute with sterile H₂O to a concentration of 0.1-1 mg/ml. Further dilutions should be made with medium containing 0.2% BSA. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized from PBS |
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Provided below are standard protocols that you may find useful for product applications.
Background
Nesfatin-1, a polypeptide produced by cleavage of the NEFA/nucleobindin-2 (NUCB2), is a secreted protein, expressed in the appetite-control hypothalamic nuclei. Nesfatin is involved in the regulation of the feeding behavior. Intracerebroventicular injection of nesfatin-1 reduces body weight in rats be affecting the animal food intake.
References
Taniguchi N.,et al.J. Biol. Chem. 275:31674-31681(2000).
Hoefig K.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
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