|Calculated MW||8.0 kDa|
|Other Names||Nesfatin 1, Nucleobindin-2, DNA-binding protein NEFA, Prepronefastin|
|Application Notes||Reconstitute with sterile H₂O to a concentration of 0.1-1 mg/ml. Further dilutions should be made with medium containing 0.2% BSA.|
|Storage||-20°C; Sterile filtered and lyophilized from PBS|
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Provided below are standard protocols that you may find useful for product applications.
Nesfatin-1, a polypeptide produced by cleavage of the NEFA/nucleobindin-2 (NUCB2), is a secreted protein, expressed in the appetite-control hypothalamic nuclei. Nesfatin is involved in the regulation of the feeding behavior. Intracerebroventicular injection of nesfatin-1 reduces body weight in rats be affecting the animal food intake.
Hirschfeld G.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Hauge X.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Oh-I S.,et al.Nature 443:709-712(2006).
Yamawaki H.,et al.Biochem. Biophys. Res. Commun. 418:676-681(2012).
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