|Calculated MW||50.0 kDa|
|Other Names||Angiostatin K1-4, Angiostatin Kringles 1-4, plasminogen|
|Storage||-80°C; In 20 mM HEPES, 150 mM NaCl, pH 7.4|
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Provided below are standard protocols that you may find useful for product applications.
Angiostatin is a proteolytic fragment of plasminogen constituting kringles 1 - 4. It is a potent angiogenesis inhibitor and the inhibition of angiogenesis by angiostatin is directly related to inhibiting the proliferation of endothelial cells. Human Angiostatin significantly inhibits bFGF-induced endothelial cell proliferation and migration at concentrations ranging from 300 nM – 1.0 µM.
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