|Calculated MW||29266 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of active TCR Alpha Peptide. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C |
|Other Names||Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA|
|Formulation||50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||TCR alpha Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow|
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