LBP, human recombinant protein
Lipopolysaccharide-binding protein, LBP, LBP human recombinant protein, LBP human, human LBP
|Calculated MW||58.0 kDa|
|Other Names||Lipopolysaccharide-binding protein, LBP, LBP human recombinant protein, LBP human, human LBP|
|Application Notes||Reconstitute in 40 µl of ultra-pure distilled H₂O. This solution can then be diluted into other aqueous buffers and stored at –20°C or –70°C for future use.|
|Storage||-20°C; Lyophilized from a concentrated protein solution (0.25 mg/ml) containing PBS, pH 7.1|
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Provided below are standard protocols that you may find useful for product applications.
Natural LBP is a 58 kDa glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophils and granulocytes. This is a His-tagged protein.
Schumann R.R.,et al.Science 249:1429-1431(1990).
Wilde C.G.,et al.J. Biol. Chem. 269:17411-17416(1994).
Hubacek J.A.,et al.Biochem. Biophys. Res. Commun. 236:427-430(1997).
Kirschning C.J.,et al.Genomics 46:416-425(1997).
Long J.Y.,et al.Sheng Wu Hua Xue Yu Sheng Wu Wu Li Jin Zhan 25:469-471(1998).
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