|Calculated MW||53372 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of BMP-3. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.|
|Other Names||Bone morphogenetic protein 3, BMP-3, Bone morphogenetic protein 3A, BMP-3A, Osteogenin, BMP3, BMP3A|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||BMP-3 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.|
|Tissue Location||Expressed in adult and fetal cartilage.|
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