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LBP, mouse recombinant protein
LBP, recombinant LBP, recombinant lipo polysaccharide binding protein
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q61805 |
|---|---|
| Calculated MW | 64.0 kDa |
| Gene ID | Mm.218846. |
|---|---|
| Gene Symbol | LBP |
| Other Names | Lipopolysaccharide-binding protein, LBP, LBP human recombinant protein, LBP human, human LBP |
| Gene Source | Mouse |
| Source | CHO cells |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; |
| Recombinant | Yes |
| Application Notes | Reconstitute in 10 µl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers and stored at –20°C or –70°C for future use. |
| Format | Lyophilized protein |
| Storage | -20°C; Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2 |
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Provided below are standard protocols that you may find useful for product applications.
Background
Natural LBP is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
References
Lengacher S.,et al.J. Inflamm. 47:165-172(1995).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Eckert J.K.,et al.Immunity 39:647-660(2013).
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