|Calculated MW||46555 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of BMP-4.|
|Other Names||Bone morphogenetic protein 4, BMP-4, Bone morphogenetic protein 2B, BMP-2B, BMP4, BMP2B, DVR4|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||BMP-4 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines|
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