sCD4, human recombinant protein
gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4, CD4mut.
|Calculated MW||51111 Da|
|Other Names||gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4, CD4mut.|
|Source||Baculovirus (Sf9 insect cells)|
|Storage||-20°C; 332 µg /ml sterile filtered solution containing 10 mM sodium phosphate buffer, pH 7.0, 300 mM NaCl and 0.01% Tween-80|
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Provided below are standard protocols that you may find useful for product applications.
CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cell with have either CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized.
Maddon P.J.,et al.Cell 42:93-104(1985).
Littman D.R.,et al.Cell 55:541-541(1988).
Ansari-Lari M.A.,et al.Genome Res. 6:314-326(1996).
Ansari-Lari M.A.,et al.Genome Res. 7:268-280(1997).
Hodge T.W.,et al.Hum. Immunol. 30:99-104(1991).
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