|Calculated MW||88051 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of BRD2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.|
|Other Names||Bromodomain-containing protein 2, Protein RING3, Brd2, Ring3|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||BRD2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly (By similarity). May play a role in spermatogenesis or folliculogenesis (By similarity).|
|Cellular Location||Nucleus. Note=Detected on chromatin and nucleosomes.|
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