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FLT4, human recombinant protein

Vascular endothelial growth factor receptor 3, Fms-like tyrosine kinase 4, Tyrosine-protein kinase r

Product info
Primary Accession P35916
Calculated MW 120 kDa
Additional Info
Gene ID 2324
Gene Symbol FLT4
Other Names Vascular endothelial growth factor receptor 3, Fms-like tyrosine kinase 4, Tyrosine-protein kinase receptor FLT4
Gene Source Human
Source Insect cells
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC; ≥90%
Recombinant Yes
Results 8-500 ng/ml.
Application Notes Reconstitute in sterile water to a concentration not less than 0.1 mg/ml. This solution can then be stored at 4°C for 2-7 days. For future use for future use; For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA) then store at –20°C. Avoid freeze-thaw cycles.
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized with no additives
Citations (0)

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The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Both VEGF family members VEGF-C and VEGF-D have been shown to bind and activate VEGFR-3/FLT-4. Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25-774 amino acids and having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding.The FLT4 is purified by proprietary chromatographic techniques.


Pajusola K.,et al.Cancer Res. 52:5738-5743(1992).
Pajusola K.,et al.Cancer Res. 53:3845-3845(1993).
Galland F.,et al.Genomics 13:475-478(1992).
Galland F.,et al.Oncogene 8:1233-1240(1993).
Lee J.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:1988-1992(1996).

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$ 190.00
$ 1,350.00
Cat# PBV10509r
(40 western blots)
Availability: 5-7days
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