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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   EDEM2 Blocking Peptide   

EDEM2 Blocking Peptide

Product Information
Primary Accession Q9BV94
Gene ID 55741
Calculated MW 64753 Da
Additional Information
Gene ID 55741
Application & Usage The peptide is used for blocking the antibody activity of EDEM2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names ER degradation-enhancing alpha-mannosidase-like protein 2, EDEM2, C20orf31, C20orf49
Target/Specificity EDEM2
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsEDEM2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EDEM2
Synonyms C20orf31, C20orf49
Function Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
Cellular Location Secreted. Endoplasmic reticulum lumen.
Tissue Location Expressed ubiquitously in all tissues tested with slightly higher levels detected in small intestine and peripheral blood leukocytes and weakest levels in brain and skeletal muscle.
Research Areas
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$ 95.00
Cat# PBV10511b
(40 western blots)
Availability: 5-7days
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