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>   home   >   Products   >   Proteins   >   IL-28, human recombinant protein   

IL-28, human recombinant protein

Interleukin-28A, IL-28A, IFN-Lambda 2, Interferon-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20.

Product info
Primary Accession Q8IZJ0
Calculated MW 19.6 kDa
Additional Info
Gene ID 282616
Gene Symbol IL28
Other Names Interleukin-28A, IL-28A, IFN-Lambda 2, Interferon-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20, Cytokine receptor family 2 member 12.
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥85%
Assay2&Purity2 HPLC; ≥85%
Recombinant Yes
Application Notes Reconstitute in sterile dH₂O not less than 100 µg/ml. This solution can then be diluted into other aqueous buffers
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized with no additives
Citations (0)

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IL-28A is distantly related to type I interferons and the IL-10 family. Expression of IL-28A is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, β (IL10RB) and interleukin 28 receptor α. IL-28A exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumour activity. IL-28A acts similarly to IFNs, but is less effective generally and has activity in a more limited range of cell lines. IL-28A induces ELR(-) CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN-γ-independent manner. IL-28A produced in response to viral infection, activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection. Recombinant human IL-28A produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids and having a molecular mass of 19.6 kDa.

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$ 3,950.00
$ 190.00
Cat# PBV10516r
(40 western blots)
Availability: 5-7days
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