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ACTH Blocking Peptide

     
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Product Information
Primary Accession P01189
Calculated MW 29424 Da
Additional Information
Gene ID 5443
Application & Usage The peptide is used for blocking the antibody activity of ACTH (Cat. No. A1051-100). It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Pro-opiomelanocortin, POMC, Corticotropin-lipotropin, NPP, Melanotropin gamma, Gamma-MSH, Potential peptide, Corticotropin, Adrenocorticotropic hormone, ACTH, Melanotropin alpha, Alpha-MSH, Corticotropin-like intermediary peptide, CLIP, Lipotropin beta, Beta-LPH, Lipotropin gamma, Gamma-LPH, Melanotropin beta, Beta-MSH, Beta-endorphin, Met-enkephalin, POMC
Target/Specificity ACTH
Formulation 50 µg (0.5 mg/ml) in PBS (pH 7.2) with 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol
Background Descriptions
PrecautionsACTH Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POMC
Function Corticotropin: Stimulates the adrenal glands to release cortisol. Melanocyte-stimulating hormone beta: Increases the pigmentation of skin by increasing melanin production in melanocytes. Met-enkephalin: Endogenous opiate.
Cellular Location Secreted {ECO:0000250|UniProtKB:P01193}. Note=Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms. {ECO:0000250|UniProtKB:P01193}
Tissue Location ACTH and MSH are produced by the pituitary gland
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$ 95.00
Cat# PBV10518b-50
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