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Prolactin Receptor, human recombinant protein

PRL-R, hPRLrI, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL R

Product info
Primary Accession P16471
Calculated MW 23.97 kDa
Additional Info
Gene ID 5618
Gene Symbol PRLR
Other Names PRL-R, hPRLrI, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL R
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥97%
Assay2&Purity2 HPLC; ≥97%
Recombinant Yes
Application Notes Reconstitute in sterile dH₂O to a concentration of 0.1 -1 mg/ml and let the lyophilized pellet dissolve completely. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Format Lyophilized protein
Storage -20°C; Lyophilized from a concentrated (0.4 mg/ml) solution with 0.0045 mM NaHCO₃
Citations (0)

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Prolactin is a pituitary hormone that plays a role in the stimulation of milk production, salt and H₂O regulation, growth, development and reproduction. The primary step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine receptors. Prolactin is a hormone involved in a range of significant functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. Prolactin exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane Prolactin receptor. PRLR varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. Recombinant human Prolactin Receptor (Extra Cellular Domain) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 210 amino acids and having a molecular mass of 23.97 kDa.


Boutin J.-M.,et al.Mol. Endocrinol. 3:1455-1461(1989).
Kline J.B.,et al.J. Biol. Chem. 274:35461-35468(1999).
Hu Z.-Z.,et al.J. Clin. Endocrinol. Metab. 84:1153-1156(1999).
Hu Z.Z.,et al.J. Biol. Chem. 276:41086-41094(2001).
Kline J.B.,et al.Mol. Endocrinol. 16:2310-2322(2002).

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$ 4,800.00
$ 190.00
Cat# PBV10523r
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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