|Calculated MW||11.7 kDa (105 aa)|
|Other Names||TXN, TRX, TRX1|
|Sequence||MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV|
|Storage||-80°C; 1 mg/ml solution in PBS (pH 7.4).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Thioredoxin (Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. It is involved in the first unique step in DNA synthesis. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation. Recombinant human thioredoxin-1 was overexpressed in E. coli and purified by using conventional chromatography techniques.
Wollman E.E.,et al.J. Biol. Chem. 263:15506-15512(1988).
Tagaya Y.,et al.EMBO J. 8:757-764(1989).
Tonissen K.F.,et al.Gene 102:221-228(1991).
Reddy P.G.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Liu A.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
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