|Calculated MW||21 kDa|
|Other Names||Human Recombinant Cyclophilin F, Peptidylprolyl isomerase F, PPIF, CYP3, Cyp-D.|
|Sequence||MGSSHHHHHH SSGLVPRGSH PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS|
|Storage||-80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT 10% glycerol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Cyclophilin F is a member of peptidyl-prolyl cis-trans isomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. It is a part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
Bergsma D.J.,et al.J. Biol. Chem. 266:23204-23214(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Johnson N.,et al.Eur. J. Biochem. 263:353-359(1999).
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