|Calculated MW||39 kDa|
|Other Names||Aldo-keto reductase family 1, member C 3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5.|
|Sequence||MGSSHHHHHH SSGLVPRGSH MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD IVLVAYSALG SQRDKRWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTA EDMKAIDGLD RNLHYFNSDS FASHPNYPYS DEY|
|Storage||-80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Aldo-keto reductase family 1 member C3 in humans is encoded by the AKR1C3 gene. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation.
Qin K.-N.,et al.J. Steroid Biochem. Mol. Biol. 46:673-679(1993).
Khanna M.,et al.J. Biol. Chem. 270:20162-20168(1995).
Khanna M.,et al.J. Steroid Biochem. Mol. Biol. 53:41-46(1995).
Lin H.-K.,et al.Mol. Endocrinol. 11:1971-1984(1997).
Suzuki-Yamamoto T.,et al.FEBS Lett. 462:335-340(1999).
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