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Human recombinant protein AKR1C3

Human Recombinant AKR1C3

     
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  • CITATIONS
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Product info
Primary Accession P42330
Concentration 1
Calculated MW 39 kDa
Additional Info
Gene ID 8644
Gene Symbol AKR1C3
Other Names Aldo-keto reductase family 1, member C 3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5.
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD IVLVAYSALG SQRDKRWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTA EDMKAIDGLD RNLHYFNSDS FASHPNYPYS DEY
Format Liquid
Storage -80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Citations (0)
citation

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Background

Aldo-keto reductase family 1 member C3 in humans is encoded by the AKR1C3 gene. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation.

References

Qin K.-N.,et al.J. Steroid Biochem. Mol. Biol. 46:673-679(1993).
Khanna M.,et al.J. Biol. Chem. 270:20162-20168(1995).
Khanna M.,et al.J. Steroid Biochem. Mol. Biol. 53:41-46(1995).
Lin H.-K.,et al.Mol. Endocrinol. 11:1971-1984(1997).
Suzuki-Yamamoto T.,et al.FEBS Lett. 462:335-340(1999).

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Discontinued
Cat# PBV10574r-100
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