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Human recombinant protein FKBP2

Human Recombinant FKBP2

     
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Product info
Primary Accession P26885
Concentration 1
Calculated MW 13.4 kDa (122 aa, 22-142 aa)
Additional Info
Gene ID 2286
Gene Symbol FKBP2
Other Names Peptidyl-prolyl cis-trans isomerase FKBP2, FKBP-13, PPIase
Gene Source Human
Source E. Coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL
Format Liquid
Storage -80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 10% glycerol.
Citations (0)

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Background

FKBP2 is part of the immunophilin protein family, which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 functions as an ER chaperone and as a component of membrane cytoskeletal scaffolds.

References

Jin Y.-J.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:6677-6681(1991).
Dilella A.G.,et al.Biochem. Biophys. Res. Commun. 189:819-823(1992).
Padilla P.I.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:2322-2327(2003).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 340.00
Cat# PBV10590r-50
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