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Human recombinant protein FKBP14

Human Recombinant FKBP14

     
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Product info
Primary Accession Q9NWM8
Concentration 1
Calculated MW 24.2 kDa (213 aa, 20-211 aa + NT His Tag)
Additional Info
Gene ID 55033
Gene Symbol FKBP14
Other Names Peptidyl-prolyl cis-trans isomerase FKBP14, FKBP22
Gene Source Human
Source E. Coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MALIPEPEVK IEVLQKPFIC HRKTKGGDLM LVHYEGYLEK DGSLFHSTHK HNNGQPIWFT LGILEALKGW DQGLKGMCVG EKRKLIIPPA LGYGKEGKGK IPPESTLIFN IDLLEIRNGP RSHESFQEMD LNDDWKLSKD EVKAYLKKEF EKHGAVVNES HHDALVEDIF DKEDEDKDGF ISAREFTYKH DEL
Format Liquid
Storage -80°C; 1 mg/ml solution in PBS (pH 7.4) containing 10% glycerol.
Citations (0)

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Background

FKBP14 enzyme accelerates the folding of proteins during protein synthesis. It contains 2 EF-hand domains and one PPIase FKBP-type domain. Truncation of the amino-terminus of FKBP14 significantly decreases peptidyl prolyl cis-trans isomerase activity, therefore suggesting that the PPIase FKBP-type domain must be located at the N-terminus.

References

Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Baumann M.,et al.Am. J. Hum. Genet. 90:201-216(2012).

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$ 315.00
Cat# PBV10591r
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