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Human recombinant protein MDH2

Human Recombinant MDH2

     
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Product info
Primary Accession P40926
Concentration 1
Calculated MW 35.2 kDa (335 aa, 25-338 aa + NT His Tag)
Additional Info
Gene ID 4191
Gene Symbol MDH2
Other Names Malate dehydrogenase 2, NAD (mitochondrial), M-MDH, MDH, MOR1
Gene Source Human
Source E. Coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MAKVAVLGAS GGIGQPLSLL LKNSPLVSRL TLYDIAHTPG VAADLSHIET KAAVKGYLGP EQLPDCLKGC DVVVIPAGVP RKPGMTRDDL FNTNATIVAT LTAACAQHCP EAMICVIANP VNSTIPITAE VFKKHGVYNP NKIFGVTTLD IVRANTFVAE LKGLDPARVN VPVIGGHAGK TIIPLISQCT PKVDFPQDQL TALTGRIQEA GTEVVKAKAG AGSATLSMAY AGARFVFSLV DAMNGKEGVV ECSFVKSQET ECTYFSTPLL LGKKGIEKNL GIGKVSSFEE KMISDAIPEL KASIKKGEDF VKTLK
Format Liquid
Storage -80°C; 1 mg/ml solution in 20 mM Tris-HCl (pH 7.5) containing 10% glycerol.
Citations (0)

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Background

MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highly expressed in the adrenal system, small intestine, heart and pancreas.

References

Hu G.,et al.Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Rush J.,et al.Nat. Biotechnol. 23:94-101(2005).

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$ 340.00
Cat# PBV10593r-50
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