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Human recombinant protein Alpha-Enolase

Human Recombinant Alpha-Enolase

     
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Product info
Primary Accession P06733
Concentration 1
Calculated MW 47.1 kDa (434 aa, 1-434 aa)
Additional Info
Gene ID 2023
Gene Symbol ENO1
Other Names Non-Neuronal Enolase (NNE); Enolase-1(ENO1); MBP-1; MYC promoter-binding protein 1; PPH; taucrystallin.
Gene Source Human
Source E. Coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Results >13 units/ml
Sequence MSILKIHARE IFDSRGNPTV EVDLFTSKGL FRAAVPSGAS TGIYEALELR DNDKTRYMGK GVSKAVEHIN KTIAPALVSK KLNVTEQEKI DKLMIEMDGT ENKSKFGANA ILGVSLAVCK AGAVEKGVPL YRHIADLAGN SEVILPVPAF NVINGGSHAG NKLAMQEFMI LPVGAANFRE AMRIGAEVYH NLKNVIKEKY GKDATNVGDE GGFAPNILEN KEGLELLKTA IGKAGYTDKV VIGMDVAASE FFRSGKYDLD FKSPDDPSRY ISPDQLADLY KSFIKDYPVV SIEDPFDQDD WGAWQKFTAS AGIQVVGDDL TVTNPKRIAK AVNEKSCNCL LLKVNQIGSV TESLQACKLA QANGWGVMVS HRSGETEDTF IADLVVGLCT GQIKTGAPCR SERLAKYNQL LRIEEELGSK AKFAGRNFRN PLAK
Format Liquid
Storage -80°C; 1 mg/ml solution in 20 mM Tris-HCl (pH 7.5) containing 10% glycerol and 1 mM MgSO4.
Citations (0)

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Background

Alpha-enolase, also known as Enolase 1, is one of three enolase isoenzymes and a glycolytic enzyme expressed in most tissues. This protein plays a key role in anaerobic metabolism under hypoxic conditions and may act as a cell surface plasminogen receptor during tissue invasion. Abnormal expression of alpha-enolase is associated with tumor progression in some cases of breast and lung cancer. It also has been identified as an auto antigen associated with Hashimoto's encephalopathy and severe asthma.

References

Giallongo A.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:6741-6745(1986).
Giallongo A.,et al.Eur. J. Biochem. 190:567-573(1990).
Ray R.,et al.Mol. Cell. Biol. 11:2154-2161(1991).
Walter M.,et al.J. Autoimmun. 8:931-945(1995).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

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$ 350.00
Cat# PBV10600r
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