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Human recombinant protein PIN4
Human Recombinant PIN4
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y237 |
|---|---|
| Concentration | 1 |
| Calculated MW | 18.8 kDa (176 aa, 1-156 aa + NT His Tag) |
| Gene ID | 5303 |
|---|---|
| Gene Symbol | PIN4 |
| Other Names | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 isoform 2, Parvulin-14, Parvulin-17, PPIase Pin4, hEPVH, PAR14, PAR17 |
| Gene Source | Human |
| Source | E. Coli |
| Assay&Purity | SDS-PAGE; ≥85% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Results | >300 nmoles/min/mg |
| Sequence | MGSSHHHHHH SSGLVPRGSH MPMAGLLKGL VRQLERFSVQ QQASKMPPKG KSGSGKAGKG GAASGSDSAD KKAQGPKGGG NAVKVRHILC EKHGKIMEAM EKLKSGMRFN EVAAQYSEDK ARQGGDLGWM TRGSMVGPFQ EAAFALPVSG MDKPVFTDPP VKTKFGYHII MVEGRK |
| Format | Liquid |
| Storage | -80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 mM PMSF, 1 mM DTT and 10% glycerol. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, Pin4 protein binds to double-stranded DNA under physiological salt conditions.
References
Rulten S.L.,et al.Biochem. Biophys. Res. Commun. 259:557-562(1999).
Uchida T.,et al.FEBS Lett. 446:278-282(1999).
Ross M.T.,et al.Nature 434:325-337(2005).
Mueller J.W.,et al.BMC Mol. Biol. 7:9-9(2006).
Kessler D.,et al.BMC Biol. 5:37-37(2007).
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