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recombinant protein hSUMO1-AMC
Recombinant hSUMO1-AMC
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P63165 |
|---|---|
| Calculated MW | 11.142 kDa |
| Gene ID | 7341 |
|---|---|
| Gene Symbol | SUMO1 |
| Gene Source | Human |
| Assay&Purity | RP-HPLC; ≥95% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Format | Lyophilized powder |
| Storage | -80°C; Lyophilized powder |
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Provided below are standard protocols that you may find useful for product applications.
Background
hSUMO1-AMC is prepared via the conjugation of 7-amino-4-methylcoumarin (AMC) to the C-terminal Gly of hSUMO1. This conjugation quenches the intrinsic fluorescence of AMC. Upon incubation with a protease recognizing hSUMOs, such as Senp1 or Senp2, AMC is released and the increase in fluorescence at 460 nm (Exc. 380 nm) can be measured. The enhanced purity of hSUMO1-AMC compared to that of other commercial vendors leads to a greater signal to noise ratio. This protein contains no extraneous tags.
References
Lapenta V.,et al.Genomics 40:362-367(1997).
Boddy M.N.,et al.Oncogene 13:971-982(1996).
Shen Z.,et al.Genomics 36:271-279(1996).
Mahajan R.,et al.Cell 88:97-107(1997).
Matunis M.J.,et al.J. Cell Biol. 135:1457-1470(1996).
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